Season 8, Episode 13: "The Comeback"

...the ocean called. They're running out of shrimp.

Oh, yeah, Reilly?

Well, the jerk store called. They're running out of you.

What's the difference? You're their all-time bestseller.

George's painstakingly-rehearsed comeback, delivered weeks too late and to the wrong audience. The definitive sitcom monument to esprit de l'escalier.